Phantom Experiments on a PSAPD-Based Compact Gamma Camera With Submillimeter Spatial Resolution for Small Animal SPECT
نویسندگان
چکیده
منابع مشابه
A clinical gamma camera-based pinhole collimated system for high resolution small animal SPECT imaging.
The main objective of the present study was to upgrade a clinical gamma camera to obtain high resolution tomographic images of small animal organs. The system is based on a clinical gamma camera to which we have adapted a special-purpose pinhole collimator and a device for positioning and rotating the target based on a computer-controlled step motor. We developed a software tool to reconstruct ...
متن کاملUse of a compact pixellated gamma camera for small animal pinhole SPECT imaging.
OBJECTIVES Pinhole SPECT which permits in vivo high resolution 3D imaging of physiological functions in small animals facilitates objective assessment of pharmaceutical development and regenerative therapy in pre-clinical trials. For handiness and mobility, the miniature size of the SPECT system is useful. We developed a small animal SPECT system based on a compact high-resolution gamma camera ...
متن کاملDetermination of Optimum Planar Imaging Parameters for Small Structures with Diameters Less Than the Resolution of the Gamma Camera
Introduction: The limited spatial resolution of the gamma camera hinders the absolute quantification of planar images of small structures. The imaged structures are affected by partial volume effects (PVEs), which can spread activity and lead to underestimation of the regional distribution. The use of optimum planar parameters reduces the impact of the limited spatial resolution of the gamma c...
متن کاملEvaluation of the performance of parallel-hole collimator for high resolution small animal SPECT: A Monte Carlo study
Introduction: Image quality and accuracy of in vivo activity quantification in SPECT are affected by collimator penetration and scatter components, especially in high energy imaging. These phenomena highly depend on the collimator characteristic and photon energy. The presence of penetrated and scattered photons from collimator in SPECT images degrades spatial resolution, contr...
متن کاملUltra-high-resolution small- animal SPECT imaging
Today the majority of clinical molecular imaging procedures are carried out with single photon emitters and gamma cameras, in planar mode and Single Photon Emission Computed Tomography (SPECT) mode. Thanks to the development of advanced multi-pinhole collimation technologies, SPECT imaging of small experimental animals is rapidly gaining in popularity. Whereas resolutions in routine clinical SP...
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ژورنال
عنوان ژورنال: IEEE Transactions on Nuclear Science
سال: 2010
ISSN: 0018-9499,1558-1578
DOI: 10.1109/tns.2010.2056386